Pharmacologic Treatments for Acute Respiratory Distress Syndrome.
Crit Care Clin
; 37(4): 877-893, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1414517
ABSTRACT
Acute respiratory distress syndrome is a heterogenous syndrome with many etiologies for which there are no definitive pharmacologic treatments, despite decades of research. We explore some adjunctive pharmacologic therapies, including neuromuscular blockade, corticosteroids, and inhaled pulmonary vasodilators. Additionally, we explore some investigative therapies, including Vitamin C, beta-agonists, statins, mesenchymal stromal cells, and granulocyte-macrophage colony stimulating factor. We do discuss the potential role of steroids in acute respiratory distress syndrome with severe acute respiratory syndrome coronavirus 2 as a trigger. The standard of care, however, remains supportive care.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Distress Syndrome
/
COVID-19
Type of study:
Etiology study
Limits:
Humans
Language:
English
Journal:
Crit Care Clin
Journal subject:
Critical Care
Year:
2021
Document Type:
Article
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