Acute COVID-19 Infection Associated With Necrotizing Disseminated Acute Leukoencephalopathy and Brain Microhemorrhages in a Pediatric Patient.

De Avila, Camila; Rauseo Lopez, Luis F; Mandelia, Yamini

De Avila, Camila; Rauseo Lopez, Luis F; Mandelia, Yamini.

De Avila C; From the East Carolina University, Vidant Medical Center, Brody School of Medicine, Greenville, NC.

Pediatr Infect Dis J ; 40(12): e493-e496, 2021 12 01.

Article in English | MEDLINE | ID: covidwho-1416156

ABSTRACT

ABSTRACT

We present a case of a 14-year-old, previously healthy female, admitted with acute coronavirus disease 2019 infection and new-onset seizures secondary to virus-associated necrotizing disseminated acute leukoencephalopathy. Her symptoms resolved completely with intravenous immunoglobulin and steroids. Pathophysiology and prognosis of neurologic manifestations of coronavirus disease 2019 remain unclear.

Subject(s)

COVID-19/complications; Intracranial Hemorrhages/etiology; Leukoencephalopathies/etiology; Leukoencephalopathies/virology; SARS-CoV-2; Adolescent; Anticonvulsants/administration & dosage; Anticonvulsants/therapeutic use; Female; Humans; Immunoglobulins, Intravenous/therapeutic use; Intracranial Hemorrhages/pathology; Leukoencephalopathies/pathology; Levetiracetam/administration & dosage; Levetiracetam/therapeutic use; Lorazepam/administration & dosage; Lorazepam/therapeutic use; Seizures/drug therapy; COVID-19 Drug Treatment

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Intracranial Hemorrhages / Leukoencephalopathies / SARS-CoV-2 / COVID-19 Type of study: Case report / Prognostic study Topics: Long Covid / Variants Limits: Adolescent / Female / Humans Language: English Journal: Pediatr Infect Dis J Journal subject: Communicable Diseases / Pediatrics Year: 2021 Document Type: Article Affiliation country: INF.0000000000003302

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