Fungal central skull-base osteomyelitis: atypical presentation and management issues.
BMJ Case Rep
; 14(9)2021 Sep 16.
Article
in English
| MEDLINE | ID: covidwho-1416638
ABSTRACT
Mucormycosis is a very commonly encountered disease in the sinonasal region in patients with diabetes and immunocompromised status specially in the northern part of the Indian continent. Due to its fulminant nature and involvement in the rhino-orbital-cerebral region, prognosis is poor even after extensive debridement and amphotericin-B therapy. We present a case with diagnosis of sarcoidosis being treated with systemic steroids who developed sudden-onset ptosis and left lateral rectus palsy. On radiological evaluation with MRI, a heterogenously peripherally enhancing lesion was seen in the nasopharynx suggestive of nasopharyngeal abscess. The patient was taken up for emergency surgery; a necrotic lesion with destruction of sphenoid bone, pterygoids and clivus was seen originating in the nasopharynx. The lesion on fungal staining came out to be broad aseptate hyphae suggestive of mucormycosis.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Osteomyelitis
/
Mucorales
/
Mucormycosis
Type of study:
Case report
/
Diagnostic study
/
Experimental Studies
/
Prognostic study
Limits:
Humans
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Bcr-2021-243530
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