Haemophagocytic lymphohistiocytosis in pregnancy: a pertinent case during the COVID-19 pandemic.
BMJ Case Rep
; 14(9)2021 Sep 17.
Article
in English
| MEDLINE | ID: covidwho-1416644
ABSTRACT
Haemophagocytic lymphohistiocytosis (HLH) is a rare, often fatal disease, and presents a diagnostic challenge in the pregnant patient. This challenge is particularly relevant during the current COVID-19 pandemic. We present a case of HLH in a pregnant woman presenting with fever predating the COVID-19 pandemic. A 33-year-old, gravida 2, para 1 at 27 weeks' gestation presented with fever, transaminitis, thrombocytopenia and elevated ferritin. After treatment according to the HLH-94 protocol, caesarean delivery and weeks of intensive care, the patient recovered fully. With prompt diagnosis and a multispecialty team at our tertiary care facility, she and her baby overcame a dire prognosis. HLH should be considered in pregnant patients presenting with a febrile illness. Particularly in cases of severe COVID-19, secondary HLH must be considered as an associated diagnosis.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Lymphohistiocytosis, Hemophagocytic
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Infant
/
Pregnancy
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Bcr-2021-244716
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