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Biological therapies, asthma and coronavirus disease 2019.
Ribeiro, Amélia; Aguiar, Rita; Morais-Almeida, Mário.
  • Ribeiro A; Allergy Center, CUF Descobertas Hospital, Lisbon.
  • Aguiar R; Pulmonology Department, Hospital Centre of Barreiro-Montijo, Barreiro, Portugal.
  • Morais-Almeida M; Allergy Center, CUF Descobertas Hospital, Lisbon.
Curr Opin Allergy Clin Immunol ; 21(6): 597-601, 2021 12 01.
Article in English | MEDLINE | ID: covidwho-1429314
ABSTRACT
PURPOSE OF REVIEW As of June 2021, coronavirus disease 2019 (COVID-19) exceeded 180 million reported cases and was responsible for almost 4 million deaths globally. Asthma affects approximately 262 million people worldwide and is an important cause of morbidity and mortality. Presently, it appears asthma is neither associated with an increased risk of contracting COVID-19 nor with a risk of severe COVID-19 or COVID-19 related death. Regarding the severe asthma patients on biologics, questions remain. The purpose of this review is to discuss the evidence regarding the relationship between asthma, biologics and COVID-19. RECENT

FINDINGS:

The available evidence does not suggest that severe asthmatics on treatment with biologics have a higher risk of severe acute respiratory syndrome coronavirus 2 infection compared to the general population. It does not appear that they have a higher risk of severe disease or COVID-19 related death either.

SUMMARY:

This review suggests that treatment with biologics for severe asthma is safe and should be maintained during the COVID-19 pandemic. However, more studies are needed to address this question and the role of biological therapy on different asthma phenotypes.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Asthma / Biological Products / SARS-CoV-2 / COVID-19 / Immunologic Factors Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Curr Opin Allergy Clin Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Asthma / Biological Products / SARS-CoV-2 / COVID-19 / Immunologic Factors Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Curr Opin Allergy Clin Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article