COVID-19 Infection in Sickle Cell Patients in a Developing Country: A Case Series.
Acta Haematol
; 145(1): 1-4, 2022.
Article
in English
| MEDLINE | ID: covidwho-1430269
ABSTRACT
Sickle cell disease is characterized by vaso-occlusive phenomena and haemolytic anaemia. There is a significant concern that the overlap of COVID-19 lung disease with acute chest syndrome that occurs in sickle cell patients may result in serious complications. Case reports of sickle cell patients with COVID-19 have been published. Here, we present a case series of COVID-19 infection in sickle cell patients in a developing country (Brazil). Only 10 patients tested positive so far for SARS-CoV-2 of 600 patients followed at our institution, of which 8 needed hospitalization (one in the intensive care unit), with no deaths. Even in a middle-income country, COVID-19 was reported to be relatively mild in sickle cell patients. In relation to risk factors, blood type O seems to confer some protection against developing severe COVID-19, a finding that could guide clinicians to adopt more clinical surveillance for patients with non-O blood type in sickle cell patients.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
ABO Blood-Group System
/
SARS-CoV-2
/
COVID-19
/
Anemia, Sickle Cell
Type of study:
Case report
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Acta Haematol
Year:
2022
Document Type:
Article
Affiliation country:
000519028
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