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Effective Preventive Strategies to Prevent Secondary Transmission of COVID-19 in Hemodialysis Unit: The First Month of Community Outbreak in Taiwan.
Chen, Chun-Yu; Ye, Jung-Jr; Huang, Ting-Shuo; Lee, Chin-Chan; Chen, Yih-Ting; Hsu, Cheng-Kai; Hsu, Heng-Jung; Sun, Chiao-Yin; Pan, Heng-Chih; Chen, Kuo-Su; Kao, Hao-Hsi; Ko, Chia-Chun; She, Yun-Hsuan; Wu, Chun-Ying; Lai, Chi-Chun; Hwang, Shang-Jyh; Wu, I-Wen.
  • Chen CY; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Ye JJ; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Huang TS; Department of Infectious Diseases, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Lee CC; Community Medicine Research Center, Department of General Surgery, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Chen YT; Department of Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Hsu CK; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Hsu HJ; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Sun CY; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Pan HC; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Chen KS; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Kao HH; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Ko CC; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • She YH; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Wu CY; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Lai CC; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
  • Hwang SJ; Department of Nephrology, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
  • Wu IW; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Healthcare (Basel) ; 9(9)2021 Sep 07.
Article in English | MEDLINE | ID: covidwho-1430831
ABSTRACT

BACKGROUND:

Dialyzed patients are vulnerable to coronavirus infection disease 2019 (COVID-19). The incidence and outcome of COVID-19 in hemodialysis (HD) patients in Taiwan remain unclear. A series of preventive measures were executed to combat COVID-19 transmission among HD patients.

METHODS:

We carried out a series of forward-looking and practical preventive strategies of COVID-19 control in our HD center. Incidences of COVID-19 of our HD unit were compared with those of national and local estimates from a community outbreak from 15 May to 30 June 2021. Prognostic factors associated with mortality were analyzed.

RESULTS:

The national incidence of COVID-19 was 0.062%; being highest in Taipei City (0.173%), followed by New Taipei City (0.161%) and Keelung (0.083%). The overall incidence in Keelung HD patients was 0.666%. One patient of our HD center contracted COVID-19 from the household; however, we have contained secondary transmission in our HD center by implementing strict preventive measures. The mortality rate of HD patients in Keelung was 66.6%. The median Ct value of HD patients was 17.53 (11.75-27.90) upon diagnosis. The deceased patients had a higher cardiac/thoracic ratio than alive (0.61 vs. 0.55, p = 0.036).

CONCLUSIONS:

Taking aggressive and proactive infection preventive measures impedes the secondary transmission of COVID-19 in HD facilities. COVID-19-associated mortality was high in HD patients, being the high cardiac-thoracic ratio, an important prognostic factor for clinical outcome of infected HD patients.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Year: 2021 Document Type: Article Affiliation country: Healthcare9091173

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Year: 2021 Document Type: Article Affiliation country: Healthcare9091173