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Guillain-Barré syndrome after AstraZeneca COVID-19-vaccination: A causal or casual association?
Introna, Alessandro; Caputo, Francesca; Santoro, Carlo; Guerra, Tommaso; Ucci, Maria; Mezzapesa, Domenico Maria; Trojano, Maria.
  • Introna A; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy. Electronic address: ale.introna@gmail.com.
  • Caputo F; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
  • Santoro C; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
  • Guerra T; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
  • Ucci M; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
  • Mezzapesa DM; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
  • Trojano M; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", piazza Giulio Cesare 11, 70100 Bari, Italy.
Clin Neurol Neurosurg ; 208: 106887, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1433072
ABSTRACT
We report a case of Guillain-Barré syndrome (GBS) following the first dose of Oxford/AstraZeneca COVID-19 vaccine with papilledema as atypical onset. As the COVID-19 vaccination campaign progresses worldwide, GBSs vaccine-related have been increasingly reported. After reviewing the available literature, considering the annual incidence of GBS, in this historical moment, the public health systems cannot afford an unjustified distrust in vaccines, caused by misinterpretation of epidemiological data. Nonetheless, it is important for clinicians to promptly recognize neurological complications potentially associated with COVID-19 vaccinations and report them to pharmacovigilance agencies.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study Topics: Vaccines Limits: Humans / Male / Middle aged Language: English Journal: Clin Neurol Neurosurg Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study Topics: Vaccines Limits: Humans / Male / Middle aged Language: English Journal: Clin Neurol Neurosurg Year: 2021 Document Type: Article