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Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients.
Abbate, Antonio; Gavin, Josh; Madanchi, Nima; Kim, Christin; Shah, Pranav R; Klein, Katherine; Boatman, Julie; Roberts, Charlotte; Patel, Seema; Danielides, Stamatina.
  • Abbate A; Division of Cardiology, Virginia Commonwealth University, Richmond, VA, United States of America. Electronic address: Antonio.abbate@vcuhealth.org.
  • Gavin J; Allergy, Immunology and Rheumatology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Madanchi N; Allergy, Immunology and Rheumatology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Kim C; Anesthesiology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Shah PR; Anesthesiology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Klein K; Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Boatman J; Infectious Disease - Virginia Commonwealth University, Richmond, VA, United States of America.
  • Roberts C; Division of Cardiology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Patel S; Allergy, Immunology and Rheumatology, Virginia Commonwealth University, Richmond, VA, United States of America.
  • Danielides S; Allergy, Immunology and Rheumatology, Virginia Commonwealth University, Richmond, VA, United States of America. Electronic address: Stamatina.danielides@vcuhealth.org.
Int J Cardiol ; 340: 119-121, 2021 10 01.
Article in English | MEDLINE | ID: covidwho-1433284
ABSTRACT
Immune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Myocarditis Type of study: Case report / Diagnostic study / Prognostic study Topics: Vaccines Limits: Adult / Child / Humans Language: English Journal: Int J Cardiol Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Myocarditis Type of study: Case report / Diagnostic study / Prognostic study Topics: Vaccines Limits: Adult / Child / Humans Language: English Journal: Int J Cardiol Year: 2021 Document Type: Article