Overview of Covid-19 Regarding the Cardiovascular Situation in the Light of Current Reports.
Cardiovasc Hematol Disord Drug Targets
; 20(3): 181-184, 2020.
Article
in English
| MEDLINE | ID: covidwho-1435708
ABSTRACT
Nowadays Coronavirus Disease 2019 (Covid-19) is increasing mortality all over the world mercilessly. We are learning almost every day about its new symptoms and that it mutates quickly. This disease has tied us up and made us desperate. The death rate from this disease has increased in patients who had pre-existing medical conditions, especially cardiovascular ones, by eliminating the angiotensin-converting enzyme (ACE)-2 receptor in the lungs. Also, ACE1 and angiotensin receptor blockers (ARB) may stimulate ACE2 expression and worse the prognosis. Intravenous infusions of ACEIs and ARBs in experimental animals increase the number of ACE2 receptors. Therefore, it may be one of the reasons that COVID-19 infects the cells of patients treating hypertension. However, most of the congress of cardiology do not recommend to discontinue these anti-hypertensive drugs. Therefore, this brief report evaluates Covid-19 in the view of cardiovascular diseases taking into account current reports and suggests some possible solutions to keep the virus under control.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Angiotensin-Converting Enzyme Inhibitors
/
Cardiovascular Diseases
/
Angiotensin Receptor Antagonists
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
Cardiovasc Hematol Disord Drug Targets
Journal subject:
Vascular Diseases
/
Cardiology
/
Hematology
/
Drug Therapy
Year:
2020
Document Type:
Article
Affiliation country:
1871529X20666200701110045
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