[Infections and inflammation in the development of stroke]. / Infektsii i vospalenie v razvitii insul'ta.
Zh Nevrol Psikhiatr Im S S Korsakova
; 121(8. Vyp. 2): 11-21, 2021.
Article
in Russian
| MEDLINE | ID: covidwho-1436430
ABSTRACT
The review systematizes data on the role of infectious diseases and systemic inflammation in the pathogenesis of stroke. Various risk factors for stroke associated with pro-inflammatory reactions and their contribution to the pathogenesis of cerebrovascular pathology are analyzed. The interaction of systemic inflammation with hemostasis disturbances and clots formation, activation of autoreactive clones of cytotoxic lymphocytes, the progression of endothelial damage, and other processes is shown. Along with infection, these factors increase the risk of stroke. The key mechanisms of the pathogenesis from the development of acute or chronic inflammation to the preconditions of stroke are presented. The mechanisms of the acting of the infectious process as a trigger factor and/or medium-term or long-term risk factors of stroke are described. A separate section is devoted to the mechanisms of developing cerebrovascular diseases after COVID-19. Identifying an increased risk of stroke due to infection can be of great preventive value. Understanding of this risk by specialists followed by correction of drug therapy and rehabilitation measures can reduce the incidence of cerebrovascular complications in infectious patients.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Stroke
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Russian
Journal:
Zh Nevrol Psikhiatr Im S S Korsakova
Journal subject:
Neurology
/
Psychiatry
Year:
2021
Document Type:
Article
Affiliation country:
Jnevro202112108211
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