[Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19].
Ter Arkh
; 93(8): 948-953, 2021 Aug 15.
Article
in Russian
| MEDLINE | ID: covidwho-1436513
ABSTRACT
A reduced supply of micronutrient vitamin D leads to a more severe course of coronavirus infection (COVID-19). Vitamin D deficiency is combined with a decrease in innate antiviral immunity and excess of inflammation. Vitamin D supplementation stimulates the synthesis of antibacterial peptides and is important for weakening the cytokine storm, reducing excessive acute and chronic inflammation, and also for compensating for chronic comorbid pathologies. Active forms of vitamin D (alfacalcidol, etc.) are of particular importance for compensating for vitamin D deficiency in elderly patients, endocrine-immune dysfunction, sarcopenia, chronic renal failure (in which the metabolism of vitamin D in the kidneys is disturbed).
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vitamin D Deficiency
/
COVID-19
Type of study:
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Humans
Language:
Russian
Journal:
Ter Arkh
Year:
2021
Document Type:
Article
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