Nanostructured Copper Surface Kills ESKAPE Pathogens and Viruses in Minutes.
ChemMedChem
; 16(23): 3553-3558, 2021 12 06.
Article
in English
| MEDLINE | ID: covidwho-1437037
ABSTRACT
In the search for a fast contact-killing antimicrobial surface to break the transmission pathway of lethal pathogens, nanostructured copper surfaces were found to exhibit the desired antimicrobial properties. Compared with plain copper, these nanostructured copper surfaces with Cu(OH)2 nano-sword or CuO nano-foam were found to completely eliminate pathogens at a fast rate, including clinically isolated drug resistant species. Additionally these nanostructured copper surfaces demonstrated potential antiviral properties when assessed against bacteriophages, as a viral surrogate, and murine hepatitis virus, a surrogate for SARS-CoV-2. The multiple modes of killing, physical killing and copper ion mediated killing contribute to the superior and fast kinetics of antimicrobial action against common microbes, and ESKAPE pathogens. Prototypes for air and water cleaning with current nanostructured copper surface have also been demonstrated.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Bacteria
/
Copper
/
Nanostructures
/
SARS-CoV-2
/
Hepatitis Viruses
/
Hydroxides
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
ChemMedChem
Journal subject:
Pharmacology
/
Chemistry
Year:
2021
Document Type:
Article
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