Your browser doesn't support javascript.
Incidence of candidaemia in prolonged venovenous extracorporeal membrane oxygenation.
Monk, E J M; Rautemaa-Richardson, R; Felton, T; Montalti, A; Parkes, M; Templeton, R; Ashworth, A; Garcia, M; Barker, J; Thomas, S.
  • Monk EJM; Department of Microbiology, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK; Infectious Diseases Service, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK. Electronic address: ejmmonk@gmail.com.
  • Rautemaa-Richardson R; Infectious Diseases Service, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK; Mycology Reference Centre Manchester (ECMM Centre of Excellence), Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK; Division of Infection, Immunity and Respi
  • Felton T; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Acute Intensive Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK; Department of Respiratory Medicine, Manchester Uni
  • Montalti A; Cardiothoracic Critical Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
  • Parkes M; Centre for Biostatistics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Templeton R; Cardiothoracic Critical Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
  • Ashworth A; Cardiothoracic Critical Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
  • Garcia M; Cardiothoracic Critical Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
  • Barker J; Cardiothoracic Critical Care Unit, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
  • Thomas S; Department of Microbiology, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
J Hosp Infect ; 119: 49-53, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1437507
ABSTRACT
This single-centre retrospective study reports the dynamics of the incidence of candida bloodstream infection (CBSI) in 145 patients receiving venovenous extracorporeal membrane oxygenation (ECMO) for respiratory support between January 2014 and December 2018. The incidence rate and odds ratio (OR) of CBSI were calculated, stratified by week of ECMO exposure. Weekly incidence increased throughout the ECMO run, with an increasing trend in OR (P=0.005), and a window of continued risk after decannulation was observed. Of the 13 patients who developed CBSI, five (38%) received empirical micafungin treatment before positive culture due to clinical suspicion. There is a need for prospective studies aiming to improve ECMO diagnostic stewardship practices and discourage unnecessary antifungal prophylaxis or empiric management.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Candidemia Type of study: Cohort study / Observational study / Prognostic study Limits: Humans Language: English Journal: J Hosp Infect Year: 2022 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Candidemia Type of study: Cohort study / Observational study / Prognostic study Limits: Humans Language: English Journal: J Hosp Infect Year: 2022 Document Type: Article