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Patient Nutrition and Probiotic Therapy in COVID-19: What Do We Know in 2021?
Hawrylkowicz, Viktoria; Lietz-Kijak, Danuta; Kazmierczak-Siedlecka, Karolina; Solek-Pastuszka, Joanna; Stachowska, Laura; Folwarski, Marcin; Parczewski, Milosz; Stachowska, Ewa.
  • Hawrylkowicz V; Department of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.
  • Lietz-Kijak D; Department of Propedeutics, Physiodiagnostics and Dental Physiotherapy, Pomeranian Medical University, 70-111 Szczecin, Poland.
  • Kazmierczak-Siedlecka K; Department of Surgical Oncology, Medical University of Gdansk, 80-214 Gdansk, Poland.
  • Solek-Pastuszka J; Department of Anaesthesiology and Intensive Care, Pomeranian Medical University, 71-242 Szczecin, Poland.
  • Stachowska L; Department of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.
  • Folwarski M; Department of Clinical Nutrition, Medical University of Gdansk, 80-211 Gdansk, Poland.
  • Parczewski M; Department of Infectious, Tropical and Acquired Immunological Diseases, Pomeranian Medical University, 71-455 Szczecin, Poland.
  • Stachowska E; Department of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.
Nutrients ; 13(10)2021 Sep 26.
Article in English | MEDLINE | ID: covidwho-1438688
ABSTRACT

BACKGROUND:

The main nutritional consequences of COVID-19 include reduced food intake, hypercatabolism, and rapid muscle wasting. Some studies showed that malnutrition is a significant problem among patients hospitalized due to COVID-19 infection, and the outcome of patients with SARS-CoV-2 is strongly associated with their nutritional status. The purpose of this study was to collect useful information about the possible elements of nutritional and probiotic therapy in patients infected with the SARS-CoV-2 virus.

METHODS:

A narrative review of the literature, including studies published up to 13 September 2021.

RESULTS:

Probiotics may support patients by inhibiting the ACE2 receptor, i.e., the passage of the virus into the cell, and may also be effective in suppressing the immune response caused by the proinflammatory cytokine cascade. In patients' diet, it is crucial to ensure an adequate intake of micronutrients, such as omega-3 fatty acids (at 2-4 g/d), selenium (300-450 µg/d) and zinc (30-50 mg/d), and vitamins A (900-700 µg/d), E (135 mg/d), D (20,000-50,000 IU), C (1-2 g/d), B6, and B12. Moreover, the daily calorie intake should amount to ≥1500-2000 with 75-100 g of protein.

CONCLUSION:

In conclusion, the treatment of gut dysbiosis involving an adequate intake of prebiotic dietary fiber and probiotics could turn out to be an immensely helpful instrument for immunomodulation, both in COVID-19 patients and prophylactically in individuals with no history of infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Nutritional Status / Probiotics / Malnutrition / Diet / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2021 Document Type: Article Affiliation country: Nu13103385

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Nutritional Status / Probiotics / Malnutrition / Diet / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2021 Document Type: Article Affiliation country: Nu13103385