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SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and Perspectives.
Long, Samuel.
  • Long S; Independent Researcher, Clarksburg, MD 20871, USA.
Viruses ; 13(10)2021 09 24.
Article in English | MEDLINE | ID: covidwho-1438746
ABSTRACT
SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis. This review summarizes the recent progress on SARS-CoV-2 sgRNA identification, characterization, and application as a viral replication marker. The significance of these findings and potential future research areas of interest are discussed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gene Expression Regulation, Viral / SARS-CoV-2 / COVID-19 Type of study: Etiology study Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: V13101923

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gene Expression Regulation, Viral / SARS-CoV-2 / COVID-19 Type of study: Etiology study Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: V13101923