SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and Perspectives.
Viruses
; 13(10)2021 09 24.
Article
in English
| MEDLINE | ID: covidwho-1438746
ABSTRACT
SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis. This review summarizes the recent progress on SARS-CoV-2 sgRNA identification, characterization, and application as a viral replication marker. The significance of these findings and potential future research areas of interest are discussed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Gene Expression Regulation, Viral
/
SARS-CoV-2
/
COVID-19
Type of study:
Etiology study
Limits:
Animals
/
Humans
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
V13101923
Similar
MEDLINE
...
LILACS
LIS