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Ethanol Susceptibility of SARS-CoV-2 and Other Enveloped Viruses.
Nomura, Toshihito; Nazmul, Tanuza; Yoshimoto, Reiko; Higashiura, Akifumi; Oda, Kosuke; Sakaguchi, Takemasa.
  • Nomura T; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
  • Nazmul T; Department of Infectious Diseases, Hiroshima University Hospital.
  • Yoshimoto R; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
  • Higashiura A; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
  • Oda K; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
  • Sakaguchi T; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Biocontrol Sci ; 26(3): 177-180, 2021.
Article in English | MEDLINE | ID: covidwho-1438814
ABSTRACT
Ethanol is an effective disinfectant against the novel coronavirus SARS-CoV-2. However, its effective concentration has not been shown, and we therefore analyzed the effects of different concentrations of ethanol on SARS-CoV-2. When SARS-CoV-2 was treated with varying ethanol concentrations and examined for changes in infectivity, the ethanol concentration at which 99% of the infectious titers were reduced was 24.1% (w/w) [29.3% (v/v)]. For reference, ethanol susceptibility was also examined with other envelope viruses, including influenza virus, vesicular stomatitis virus in the family Rhabdoviridae, and Newcastle disease virus in the family Paramyxoviridae, and the 99% inhibitory concentrations were found to be 28.8%(w/w) [34.8% (v/v)], 24.0% (w/w) [29.2% (v/v)], and 13.3% (w/w) [16.4% (v/v)], respectively. Some differences from SARS-CoV-2 were observed, but the differences were not significant. It was concluded that ethanol at a concentration of 30%(w/w) [36.2% (v/v)] almost completely inactivates SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Disinfectants / Ethanol / SARS-CoV-2 Limits: Humans Language: English Journal: Biocontrol Sci Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Disinfectants / Ethanol / SARS-CoV-2 Limits: Humans Language: English Journal: Biocontrol Sci Year: 2021 Document Type: Article