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The Trends of Uveal Melanoma Research in the Past Two Decades and Future Perspectives.
Elubous, Khaled Ali; Alebous, Ali D; Abous, Hebah A; Elubous, Rawan A.
  • Elubous KA; Department of Ophthalmology, University of Jordan, Amman, Jordan.
  • Alebous AD; Department of Surgery, King Hussein Cancer Center, Amman, Jordan.
  • Abous HA; Department of Dermatology, Jordanian Royal Medical Services, Amman, Jordan.
  • Elubous RA; Department of Radiology, University of Jordan, Amman, Jordan.
SN Compr Clin Med ; 3(12): 2593-2602, 2021.
Article in English | MEDLINE | ID: covidwho-1439808
ABSTRACT
Evaluation of the research trends in uveal melanoma in the past two decades. Data were extracted from the Web of Science database website. VOSviewer and Citespace software were used to analyze the retrieved data. The leading country in terms of output and international collaboration is the USA. Research interest in genetic mutations, molecular pathways, and immunotherapy was remarkable in recent years. Most of the top ten journals are specialized in ophthalmology. In recent years, the hotspots include future perspectives, BAP1 mutation, therapeutic target, and systematic reviews. The keywords with the strongest citation bursts are immunotherapy, outcome, and in situ hybridization. The output of uveal melanoma research increased during the past two decades. Before 2015, the main focus of the research was to facilitate prognostication and metastatic risk stratification. Recently, research has moved to examine the metastatic microenvironment. Future research foci may include exploring the role of different mutations, immunotherapy, molecular alterations, and finding ideal clinical biomarkers.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: SN Compr Clin Med Year: 2021 Document Type: Article Affiliation country: S42399-021-01068-y

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: SN Compr Clin Med Year: 2021 Document Type: Article Affiliation country: S42399-021-01068-y