Delayed admissions and efficacy of steroid use in patients with critical and severe COVID-19: an apprehensive approach.
J Public Health (Oxf)
; 43(Suppl 3): iii43-iii48, 2021 12 08.
Article
in English
| MEDLINE | ID: covidwho-1440643
ABSTRACT
BACKGROUND:
Inadvertent delays in access to appropriate therapeutic interventions in high-risk group coronavirus disease 2019 (COVID-19) patients contribute to mortality in patients with severe/critical disease presentation.OBJECTIVES:
The aim of this study was to determine the effect of timely admission to the hospital on mortality of patients with severe/critical COVID-19. Another secondary aspect of this study was to observe the efficacy of time-dependent use of corticosteroids on mortality of critical/severe COVID-19 patients.METHODS:
Clinical data of 659 patients with severe/critical COVID-19, admitted to four major tertiary care hospitals from the Islamabad-Rawalpindi region of Pakistan was retrospectively collected from a period February-August 2020. Multivariate logistic regression analysis was carried out to determine the predictors of mortality in severe/critical COVID-19 patients.RESULTS:
Out of a total of 659 patients, 469 (71.2%) patients died. Age > 60 years, presence of hypertension, heart disease and kidney disease along with late admission (>5 days) were significant predictors of mortality in patients with severe/critical COVID-19.CONCLUSIONS:
The study highlights the importance of well-timed provision of appropriate medical interventions control COVID-19-associated mortality.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Middle aged
Language:
English
Journal:
J Public Health (Oxf)
Year:
2021
Document Type:
Article
Affiliation country:
Pubmed
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