Acute Invasive Fungal Rhinosinusitis and Coronavirus Disease 2019.
J Craniofac Surg
; 32(8): e827-e830, 2021.
Article
in English
| MEDLINE | ID: covidwho-1440702
ABSTRACT
ABSTRACT Acute invasive fungal rhinosinusitis (mucormycosis) is a rare, highly fatal disease. This opportunistic fungal infection causes angioinvasion and ischemic tissue necrosis. It mainly affects immunocompromised patients. Since the coronavirus disease 2019 (COVID-19) outbreak, many case reports have described the rhino-orbital-cerebral mucormycosis associated with COVID-19. However, the underlying predisposing factors are unknown. Several factors, other than diabetes, which is the most well-known contributing factor, may be involved in causing this severe fungal infection in COVID-19 patients. These factors may include steroid therapy, which is being used in severely dyspneic patients, the use of broad-spectrum antibiotics that may cause fungal flare-ups, and hospitalization with possible nosocomial infections. In addition, increased serum ferritin levels, possible endothelial damage, and pancreatic islets affection among COVID-19 patients may be implicated. Head and neck surgeons should be aware of the increasing prevalence of craniofacial mucormycosis among COVID-19 patients, as early diagnosis and prompt treatment are essential to improve the outcomes.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Orbital Diseases
/
Sinusitis
/
COVID-19
/
Mucormycosis
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
Limits:
Humans
Language:
English
Journal:
J Craniofac Surg
Journal subject:
Dentistry
Year:
2021
Document Type:
Article
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