Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia.
BMC Pulm Med
; 21(1): 307, 2021 Sep 27.
Article
in English
| MEDLINE | ID: covidwho-1440925
ABSTRACT
BACKGROUND:
The main clinical consequences of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection are pneumonia and respiratory failure even requiring mechanical ventilation. In this context, the lung parenchyma is highly prone to ventilator-related injury, with pneumothorax and persistent air leak as the most serious adverse events. So far, endobronchial valve (EBV) positioning has proved efficacious in treating air leaks with a high success rate. CASE PRESENTATION We report, for the first time, two cases of patients affected by SARS-CoV-2-related pneumonia complicated with bacterial super-infection, experiencing pneumothorax and persistent air leaks after invasive mechanical ventilation. Despite the severity of respiratory failure both patients underwent rigid interventional bronchoscopy and were successfully treated through EBV positioning.CONCLUSIONS:
Persistent air leaks may result from lung tissue damage due to a complex interaction between inflammation and ventilator-related injury (VILI), especially in the advanced stages of ARDS. EBV positioning seems to be a feasible and effective minimally invasive therapeutic option for treating this subset of patients.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pleural Diseases
/
Pneumothorax
/
Respiration, Artificial
/
Bronchial Fistula
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
BMC Pulm Med
Year:
2021
Document Type:
Article
Affiliation country:
S12890-021-01653-W
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