Rapid reinfection with SARS-CoV-2 variant-of-concern Alpha detected in a nurse during an outbreak at a non-covid inpatient ward: lessons learned.
Antimicrob Resist Infect Control
; 10(1): 137, 2021 09 26.
Article
in English
| MEDLINE | ID: covidwho-1440955
ABSTRACT
We describe the lessons learned during a SARS-CoV-2 variant-of-concern Alpha outbreak investigation at a normal care unit in a university hospital in Amsterdam in December 2020. The outbreak consisted of nine nurses and two roomed-in patient family members. (attack rate 18%). One nurse tested positive with a phylogenetically distinct variant, after a documented infection 83 days prior. Three key points were taken from this investigation. First, it was controlled by adherence to existing guidelines, despite increased transmissibility of the variant. Second, viral sequencing can inform transmission cluster inference, but the epidemiological context is essential to draw appropriate conclusions. Third, reinfections with Alpha variants can occur rapidly after primary infection.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Reinfection
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Variants
Limits:
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Antimicrob Resist Infect Control
Year:
2021
Document Type:
Article
Affiliation country:
S13756-021-01008-4
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