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Vitamin D and COVID-19: An Overview of Recent Evidence.
Ghelani, Drishti; Alesi, Simon; Mousa, Aya.
  • Ghelani D; Monash Centre for Health Research and Implementation (MCHRI), Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC 3168, Australia.
  • Alesi S; Monash Centre for Health Research and Implementation (MCHRI), Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC 3168, Australia.
  • Mousa A; Monash Centre for Health Research and Implementation (MCHRI), Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC 3168, Australia.
Int J Mol Sci ; 22(19)2021 Sep 29.
Article in English | MEDLINE | ID: covidwho-1444231
ABSTRACT
The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has progressed rapidly from an outbreak to a global pandemic, with new variants rapidly emerging. Coronavirus disease 2019 (COVID-19), the disease resulting from SARS-CoV-2 infection, can lead to multiorgan damage. Due to the extremely contagious and fatal nature of the virus, it has been a priority of medical research to find effective means of treatment. Amid this search, the role of vitamin D in modulating various aspects of the innate and adaptive immune system has been discussed. This review aims to consolidate the research surrounding the role of vitamin D in the treatment and prevention of COVID-19. While there are some conflicting results reported, the consensus is that vitamin D has a host of immunomodulatory effects which may be beneficial in the context of COVID-19 and that low levels of vitamin D can result in dysfunction of crucial antimicrobial effects, potentially contributing to poor prognosis. Studies also show that the effects of low vitamin D can be mitigated via supplementation, although the benefits of vitamin D supplementation in the treatment of COVID-19 remain controversial.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vitamin D / Vitamins / COVID-19 / Immunologic Factors Type of study: Prognostic study Topics: Variants Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Ijms221910559

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vitamin D / Vitamins / COVID-19 / Immunologic Factors Type of study: Prognostic study Topics: Variants Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Ijms221910559