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Direct and Indirect Proof of SARS-CoV-2 Infections in Indigenous Wiwa Communities in North-Eastern Colombia-A Cross-Sectional Assessment Providing Preliminary Surveillance Data.
Concha, Gustavo; Frickmann, Hagen; Oey, Anke; Strengert, Monika; Kreienbrock, Lothar; Kann, Simone.
  • Concha G; Organization Wiwa Yugumaiun Bunkauanarrua Tayrona (OWYBT), Department Health Advocacy, Valledupar 2000001, Colombia.
  • Frickmann H; Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, Germany.
  • Oey A; Institute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.
  • Strengert M; Institute for Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
  • Kreienbrock L; Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
  • Kann S; TWINCORE Centre for Experimental and Clinical Infection Research, 30625 Hannover, Germany.
Vaccines (Basel) ; 9(10)2021 Oct 01.
Article in English | MEDLINE | ID: covidwho-1444355
ABSTRACT
To provide initial data on local SARS-CoV-2 epidemiology and spread in indigenous communities in north-eastern Colombia, respiratory swabs and serum samples from volunteers of indigenous communities were examined in March and April 2021. Samples from non-indigenous Colombians from the same villages were included as well. While previous exposure to SARS-CoV-2 was assessed by analysing serum samples for IgG and IgM with a rapid antibody point-of-care-test (POCT), screening for active infections was carried out with an antigen POCT test and real-time PCR from nasal swabs. In 380 indigenous and 72 non-indigenous volunteers, 61 (13.5%) active infections and an additional 113 (25%) previous infections were identified using diagnostic serology and molecular assays. Previous infections were more frequent in non-indigenous volunteers, and relevant associations of clinical features with active or previous SARS-CoV-2 infections were not observed. Symptoms reported were mild to moderate. SARS-CoV-2 was frequent in the assessed Colombian indigenous communities, as 38.5% of the study participants showed signs of exposure to SARS-CoV-2, which confirms the need to include these indigenous communities in screening and vaccination programs.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prevalence study / Randomized controlled trials / Risk factors / Screening study Topics: Vaccines Country/Region as subject: South America / Colombia Language: English Year: 2021 Document Type: Article Affiliation country: Vaccines9101120

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prevalence study / Randomized controlled trials / Risk factors / Screening study Topics: Vaccines Country/Region as subject: South America / Colombia Language: English Year: 2021 Document Type: Article Affiliation country: Vaccines9101120