Statistical Estimation of the Reproductive Number From Case Notification Data.
Am J Epidemiol
; 190(4): 611-620, 2021 04 06.
Article
in English
| MEDLINE | ID: covidwho-1447566
ABSTRACT
The reproductive number, or reproduction number, is a valuable metric in understanding infectious disease dynamics. There is a large body of literature related to its use and estimation. In the last 15 years, there has been tremendous progress in statistically estimating this number using case notification data. These approaches are appealing because they are relevant in an ongoing outbreak (e.g., for assessing the effectiveness of interventions) and do not require substantial modeling expertise to be implemented. In this article, we describe these methods and the extensions that have been developed. We provide insight into the distinct interpretations of the estimators proposed and provide real data examples to illustrate how they are implemented. Finally, we conclude with a discussion of available software and opportunities for future development.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Disease Outbreaks
/
Infections
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Am J Epidemiol
Year:
2021
Document Type:
Article
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