Your browser doesn't support javascript.
A Case Series of Acute Pericarditis following COVID-19 Vaccination in the Context of Recent Reports from Europe and the United States
Vaccine ; 2021.
Article in English | EuropePMC | ID: covidwho-1451636
ABSTRACT
<h4>Background</h4> COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9). <h4>Methods</h4> All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines. <h4>Findings</h4> Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8±10.2 years and the men/women ratio 3/5. All events resolved without sequelae;two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases. <h4>Interpretation</h4> Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity.
Search on Google
Collection: Databases of international organizations Database: EuropePMC Topics: Vaccines Language: English Journal: Vaccine Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Collection: Databases of international organizations Database: EuropePMC Topics: Vaccines Language: English Journal: Vaccine Year: 2021 Document Type: Article