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An Insight into Nanomedicinal Approaches to Combat Viral Zoonoses.
Minakshi, Prasad; Ghosh, Mayukh; Kumar, Rajesh; Brar, Basanti; Lambe, Upendra P; Banerjee, Somesh; Ranjan, Koushlesh; Kumar, Balvinder; Goel, Parveen; Malik, Yashpal S; Prasad, Gaya.
  • Minakshi P; Department of Animal Biotechnology, LLR University of Veterinary and Animal Sciences, Hisar-125001, Haryana, 125004, India.
  • Ghosh M; Department of Veterinary Physiology and Biochemistry, RGSC, Banaras Hindu University, Mirzapur (UP) - 231001, India.
  • Kumar R; Department of Veterinary Physiology and Biochemistry, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar-125001, Haryana, 125004, India.
  • Brar B; Department of Animal Biotechnology, LLR University of Veterinary and Animal Sciences, Hisar-125001, Haryana, 125004, India.
  • Lambe UP; Department of Animal Biotechnology, LLR University of Veterinary and Animal Sciences, Hisar-125001, Haryana, 125004, India.
  • Banerjee S; Department of Veterinary Microbiology, Immunology Section, LUVAS, Hisar-125004, India.
  • Ranjan K; Department of Veterinary Physiology and Biochemistry, Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, 250110, India.
  • Kumar B; ICAR-NRCE, Hisar, Haryana, 125001, India.
  • Goel P; Department of Veterinary Medicine, LLR University of Veterinary and Animal Sciences, Hisar, Haryana, 125004, India.
  • Malik YS; Division of Standardisation, Indian Veterinary Research Institute Izatnagar - Bareilly (UP) - 243122, India.
  • Prasad G; Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, UP, 250110, India.
Curr Top Med Chem ; 20(11): 915-962, 2020.
Article in English | MEDLINE | ID: covidwho-1453165
Semantic information from SemMedBD (by NLM)
1. Prophylactic treatment TREATS Zoonoses
Subject
Prophylactic treatment
Predicate
TREATS
Object
Zoonoses
2. Prophylactic treatment TREATS Zoonoses
Subject
Prophylactic treatment
Predicate
TREATS
Object
Zoonoses
ABSTRACT

BACKGROUND:

Emerging viral zoonotic diseases are one of the major obstacles to secure the "One Health" concept under the current scenario. Current prophylactic, diagnostic and therapeutic approaches often associated with certain limitations and thus proved to be insufficient for customizing rapid and efficient combating strategy against the highly transmissible pathogenic infectious agents leading to the disastrous socio-economic outcome. Moreover, most of the viral zoonoses originate from the wildlife and poor knowledge about the global virome database renders it difficult to predict future outbreaks. Thus, alternative management strategy in terms of improved prophylactic vaccines and their delivery systems; rapid and efficient diagnostics and effective targeted therapeutics are the need of the hour.

METHODS:

Structured literature search has been performed with specific keywords in bibliographic databases for the accumulation of information regarding current nanomedicine interventions along with standard books for basic virology inputs.

RESULTS:

Multi-arrayed applications of nanomedicine have proved to be an effective alternative in all the aspects regarding the prevention, diagnosis, and control of zoonotic viral diseases. The current review is focused to outline the applications of nanomaterials as anti-viral vaccines or vaccine/drug delivery systems, diagnostics and directly acting therapeutic agents in combating the important zoonotic viral diseases in the recent scenario along with their potential benefits, challenges and prospects to design successful control strategies.

CONCLUSION:

This review provides significant introspection towards the multi-arrayed applications of nanomedicine to combat several important zoonotic viral diseases.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Viral Vaccines / Drug Delivery Systems / Viral Zoonoses Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: Curr Top Med Chem Journal subject: Chemistry Year: 2020 Document Type: Article Affiliation country: 1568026620666200325114400

Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Viral Vaccines / Drug Delivery Systems / Viral Zoonoses Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: Curr Top Med Chem Journal subject: Chemistry Year: 2020 Document Type: Article Affiliation country: 1568026620666200325114400