An Insight into Nanomedicinal Approaches to Combat Viral Zoonoses.
Curr Top Med Chem
; 20(11): 915-962, 2020.
Article
in English
| MEDLINE | ID: covidwho-1453165
ABSTRACT
BACKGROUND:
Emerging viral zoonotic diseases are one of the major obstacles to secure the "One Health" concept under the current scenario. Current prophylactic, diagnostic and therapeutic approaches often associated with certain limitations and thus proved to be insufficient for customizing rapid and efficient combating strategy against the highly transmissible pathogenic infectious agents leading to the disastrous socio-economic outcome. Moreover, most of the viral zoonoses originate from the wildlife and poor knowledge about the global virome database renders it difficult to predict future outbreaks. Thus, alternative management strategy in terms of improved prophylactic vaccines and their delivery systems; rapid and efficient diagnostics and effective targeted therapeutics are the need of the hour.METHODS:
Structured literature search has been performed with specific keywords in bibliographic databases for the accumulation of information regarding current nanomedicine interventions along with standard books for basic virology inputs.RESULTS:
Multi-arrayed applications of nanomedicine have proved to be an effective alternative in all the aspects regarding the prevention, diagnosis, and control of zoonotic viral diseases. The current review is focused to outline the applications of nanomaterials as anti-viral vaccines or vaccine/drug delivery systems, diagnostics and directly acting therapeutic agents in combating the important zoonotic viral diseases in the recent scenario along with their potential benefits, challenges and prospects to design successful control strategies.CONCLUSION:
This review provides significant introspection towards the multi-arrayed applications of nanomedicine to combat several important zoonotic viral diseases.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Viruses
/
Viral Vaccines
/
Drug Delivery Systems
/
Viral Zoonoses
Type of study:
Diagnostic study
/
Prognostic study
Topics:
Vaccines
Limits:
Animals
/
Humans
Language:
English
Journal:
Curr Top Med Chem
Journal subject:
Chemistry
Year:
2020
Document Type:
Article
Affiliation country:
1568026620666200325114400
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