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Renal involvement in COVID-19: focus on kidney transplant sector.
Sagnelli, Caterina; Sica, Antonello; Gallo, Monica; Peluso, Gaia; Varlese, Filippo; D'Alessandro, Vincenzo; Ciccozzi, Massimo; Crocetto, Felice; Garofalo, Carlo; Fiorelli, Alfonso; Iannuzzo, Gabriella; Reginelli, Alfonso; Schonauer, Fabrizo; Santangelo, Michele; Sagnelli, Evangelista; Creta, Massimiliano; Calogero, Armando.
  • Sagnelli C; Department of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania "Luigi Vanvitelli", Largo Madonna delle Grazie n. 1, 80138, Naples, Italy.
  • Sica A; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80131, Naples, Italy.
  • Gallo M; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131, Naples, Italy.
  • Peluso G; Department of Advanced Biomedical Sciences, University of Naples Federico II, via Pansini, 5, 80131, Naples, Italy.
  • Varlese F; Department of Advanced Biomedical Sciences, University of Naples Federico II, via Pansini, 5, 80131, Naples, Italy.
  • D'Alessandro V; UOSD Centro Trapianti di rene e Chirurgia del Retroperitoneo, AOU-University of Naples Federico II, 80131, Naples, Italy.
  • Ciccozzi M; Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, 80128, Rome, Italy.
  • Crocetto F; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131, Naples, Italy.
  • Garofalo C; Division of Nephrology, University of Campania "Luigi Vanvitelli", 80137, Naples, Italy.
  • Fiorelli A; Department of Thoracic Surgery, University of Campania "Luigi Vanvitelli", 80137, Naples, Italy.
  • Iannuzzo G; Department of Clinical Medicine and Surgery, Federico II University Naples, Naples, Italy.
  • Reginelli A; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80131, Naples, Italy.
  • Schonauer F; Division of Plastic, Reconstructive and Aesthetic Surgery, University of Naples Federico II, 80131, Naples, Italy.
  • Santangelo M; Department of Advanced Biomedical Sciences, University of Naples Federico II, via Pansini, 5, 80131, Naples, Italy.
  • Sagnelli E; Department of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania "Luigi Vanvitelli", Largo Madonna delle Grazie n. 1, 80138, Naples, Italy. evangelista.sagnelli@unicampania.it.
  • Creta M; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131, Naples, Italy.
  • Calogero A; Department of Advanced Biomedical Sciences, University of Naples Federico II, via Pansini, 5, 80131, Naples, Italy.
Infection ; 49(6): 1265-1275, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1453923
ABSTRACT

INTRODUCTION:

Kidney transplant recipients and patients on the waiting list for kidney transplant who acquire SARS-CoV-2 infection are at serious risk of developing severe COVID-19, with an increased risk of mortality for the their immunosuppressive state; other risk factors for mortality have been identified in some comorbidities such as obesity, diabetes, asthma and chronic lung disease. MATERIALS AND

METHODS:

The COVID-19 pandemic has led to a sharp reduction in kidney transplants in most countries, mainly due to the concern of patients on the waiting list for their potential increased susceptibility to acquire SARS-CoV-2 infection in healthcare facilities and for the difficulties of transplant centers to ensure full activity as hospitals have had to focus most of their attention on COVID-19 patients. Indeed, while the infection curve continued its exponential rise, there was a vertical decline in kidney donation/transplant activity.

CONCLUSION:

This review article focuses on the damage induced by SARS-CoV-2 infection on kidney and on the adverse effect of this pandemic on the entire kidney transplant sector.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Kidney Transplantation / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Infection Year: 2021 Document Type: Article Affiliation country: S15010-021-01706-6

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Kidney Transplantation / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Infection Year: 2021 Document Type: Article Affiliation country: S15010-021-01706-6