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Impact of Body Mass Index on Perioperative Complications and Oncologic Outcomes in Patients Undergoing Thermal Ablation for Renal Cell Carcinoma.
Zhou, Wenhui; Herwald, Sanna E; Uppot, Raul N; Arellano, Ronald S.
  • Zhou W; Department of Radiology, Stanford Medicine, Stanford, California.
  • Herwald SE; Department of Radiology, Stanford Medicine, Stanford, California.
  • Uppot RN; Department of Interventional Radiology, Massachusetts General Hospital, 55 Fruit Street, GRB 293, Boston, MA 02114.
  • Arellano RS; Department of Interventional Radiology, Massachusetts General Hospital, 55 Fruit Street, GRB 293, Boston, MA 02114. Electronic address: RARELLANO@mgh.harvard.edu.
J Vasc Interv Radiol ; 32(1): 33-38, 2021 01.
Article in English | MEDLINE | ID: covidwho-1454337
Semantic information from SemMedBD (by NLM)
1. Ablation TREATS Patients
Subject
Ablation
Predicate
TREATS
Object
Patients
2. Patients LOCATION_OF IMPACT gene
Subject
Patients
Predicate
LOCATION_OF
Object
IMPACT gene
3. Body mass index procedure AFFECTS Perioperative complication
Subject
Body mass index procedure
Predicate
AFFECTS
Object
Perioperative complication
4. Ablation TREATS Renal Cell Carcinoma
Subject
Ablation
Predicate
TREATS
Object
Renal Cell Carcinoma
5. Ablation TREATS Male population group
Subject
Ablation
Predicate
TREATS
Object
Male population group
6. Ablation TREATS Woman
Subject
Ablation
Predicate
TREATS
Object
Woman
7. Ablation TREATS Conventional (Clear Cell) Renal Cell Carcinoma
Subject
Ablation
Predicate
TREATS
Object
Conventional (Clear Cell) Renal Cell Carcinoma
8. Residual Tumor PROCESS_OF Cohort
Subject
Residual Tumor
Predicate
PROCESS_OF
Object
Cohort
9. Obesity PROCESS_OF Patients
Subject
Obesity
Predicate
PROCESS_OF
Object
Patients
10. Ablation TREATS Patients
Subject
Ablation
Predicate
TREATS
Object
Patients
11. Patients LOCATION_OF IMPACT gene
Subject
Patients
Predicate
LOCATION_OF
Object
IMPACT gene
12. Body mass index procedure AFFECTS Perioperative complication
Subject
Body mass index procedure
Predicate
AFFECTS
Object
Perioperative complication
13. Ablation TREATS Renal Cell Carcinoma
Subject
Ablation
Predicate
TREATS
Object
Renal Cell Carcinoma
14. Ablation TREATS Male population group
Subject
Ablation
Predicate
TREATS
Object
Male population group
15. Ablation TREATS Woman
Subject
Ablation
Predicate
TREATS
Object
Woman
16. Ablation TREATS Conventional (Clear Cell) Renal Cell Carcinoma
Subject
Ablation
Predicate
TREATS
Object
Conventional (Clear Cell) Renal Cell Carcinoma
17. Residual Tumor PROCESS_OF Cohort
Subject
Residual Tumor
Predicate
PROCESS_OF
Object
Cohort
18. Obesity PROCESS_OF Patients
Subject
Obesity
Predicate
PROCESS_OF
Object
Patients
ABSTRACT

PURPOSE:

To determine effect of body mass index (BMI) on safety and cancer-related outcomes of thermal ablation for renal cell carcinoma (RRC). MATERIALS AND

METHODS:

This retrospective study evaluated 427 patients (287 men and 140 women; mean [SD] age, 72 [12] y) who were treated with thermal ablation for RCC between October 2006 and December 2017. Patients were stratified by BMI into 3 categories normal weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), and obese (≥ 30 kg/m2). Of 427 patients, 71 (16%) were normal weight, 157 (37%) were overweight, and 199 (47%) were obese. Complication rates, local recurrence, and residual disease were compared in the 3 cohorts.

RESULTS:

No differences in technical success between normal-weight, overweight, and obese patients were identified (P = .72). Primary technique efficacy rates for normal-weight, overweight, and obese patients were 91%, 94%, and 93% (P = .71). There was no significant difference in RCC specific-free survival, disease-free survival, and metastasis-free survival between obese, overweight, and normal-weight groups (P = .72, P = .43, P = .99). Complication rates between the 3 cohorts were similar (normal weight 4%, overweight 2%, obese 3%; P = .71).

CONCLUSIONS:

CT-guided renal ablation is safe, feasible, and effective regardless of BMI.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Type of study: Observational study Language: English Journal: J Vasc Interv Radiol Clinical aspect: Diagnosis / Etiology / Therapy Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Type of study: Observational study Language: English Journal: J Vasc Interv Radiol Clinical aspect: Diagnosis / Etiology / Therapy Year: 2021
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