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Impact of Body Mass Index on Perioperative Complications and Oncologic Outcomes in Patients Undergoing Thermal Ablation for Renal Cell Carcinoma.
Zhou, Wenhui; Herwald, Sanna E; Uppot, Raul N; Arellano, Ronald S.
  • Zhou W; Department of Radiology, Stanford Medicine, Stanford, California.
  • Herwald SE; Department of Radiology, Stanford Medicine, Stanford, California.
  • Uppot RN; Department of Interventional Radiology, Massachusetts General Hospital, 55 Fruit Street, GRB 293, Boston, MA 02114.
  • Arellano RS; Department of Interventional Radiology, Massachusetts General Hospital, 55 Fruit Street, GRB 293, Boston, MA 02114. Electronic address: RARELLANO@mgh.harvard.edu.
J Vasc Interv Radiol ; 32(1): 33-38, 2021 01.
Article in English | MEDLINE | ID: covidwho-1454337
ABSTRACT

PURPOSE:

To determine effect of body mass index (BMI) on safety and cancer-related outcomes of thermal ablation for renal cell carcinoma (RRC). MATERIALS AND

METHODS:

This retrospective study evaluated 427 patients (287 men and 140 women; mean [SD] age, 72 [12] y) who were treated with thermal ablation for RCC between October 2006 and December 2017. Patients were stratified by BMI into 3 categories normal weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), and obese (≥ 30 kg/m2). Of 427 patients, 71 (16%) were normal weight, 157 (37%) were overweight, and 199 (47%) were obese. Complication rates, local recurrence, and residual disease were compared in the 3 cohorts.

RESULTS:

No differences in technical success between normal-weight, overweight, and obese patients were identified (P = .72). Primary technique efficacy rates for normal-weight, overweight, and obese patients were 91%, 94%, and 93% (P = .71). There was no significant difference in RCC specific-free survival, disease-free survival, and metastasis-free survival between obese, overweight, and normal-weight groups (P = .72, P = .43, P = .99). Complication rates between the 3 cohorts were similar (normal weight 4%, overweight 2%, obese 3%; P = .71).

CONCLUSIONS:

CT-guided renal ablation is safe, feasible, and effective regardless of BMI.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: J Vasc Interv Radiol Journal subject: Vascular Diseases / Radiology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Carcinoma, Renal Cell / Body Mass Index / Cryosurgery / Radiofrequency Ablation / Kidney Neoplasms / Microwaves / Obesity Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: J Vasc Interv Radiol Journal subject: Vascular Diseases / Radiology Year: 2021 Document Type: Article