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Evaluation of Prognosis of Coma Patients With Acute Brain Injury by Electroencephalogram Bispectral Index Monitoring.
Shi, Dan; Shen, Chen; Wu, Jiayu; Xu, Feng; Feng, Zhizhong; Xiang, Dingchao; Li, Jianjun; Chen, Junhui.
  • Shi D; Department of Neurology, The Fifth People's Hospital of Wuxi City, Wuxi, Jiangsu Province, China (Mr Shi); Departments of Neurosurgery (Mss Shen and Xu, Messrs Feng and Xiang, and Dr Chen) and Neurology (Ms Wu), 904th Hospital of Joint Logistic Support Force of PLA, Wuxi, Jiangsu Province, China; and Department of Nephrology, People's Hospital of Huishan District, Wuxi, Jiangsu Province, China (Mr Li).
J Trauma Nurs ; 28(5): 298-303, 2021.
Article in English | MEDLINE | ID: covidwho-1455396
ABSTRACT

BACKGROUND:

The high mortality rate of comatose patients with traumatic brain injury is a prominent public health issue that negatively impacts patients and their families. Objective, reliable tools are needed to guide treatment decisions and prioritize resources.

OBJECTIVE:

This study aimed to evaluate the prognostic value of the bispectral index (BIS) in comatose patients with severe brain injury.

METHODS:

This was a retrospective cohort study of 84 patients with severe brain injury and Glasgow Coma Scale (GCS) scores of 8 and less treated from January 2015 to June 2017. Sedatives were withheld at least 24 hr before BIS scoring. The BIS value, GCS scores, and Full Outline of UnResponsiveness (FOUR) were monitored hourly for 48 hr. Based on the Glasgow Outcome Scale (GOS) score, the patients were divided into poor (GOS score 1-2) and good prognosis groups (GOS score 3-5). The correlation between BIS and prognosis was analyzed by logistic regression, and the receiver operating characteristic curves were plotted.

RESULTS:

The mean (SD) of the BIS value 54.63 (11.76), p = .000; and GCS score 5.76 (1.87), p = .000, were higher in the good prognosis group than in the poor prognosis group. Lower BIS values and GCS scores were correlated with poorer prognosis. Based on the area under the curve of receiver operating characteristic curves, the optimal diagnostic cutoff value of the BIS was 43.6, and the associated sensitivity and specificity were 85.4% and 74.4%, respectively.

CONCLUSION:

Taken together, our study indicates that BIS had good predictive value on prognosis. These findings suggested that BIS could be used to evaluate the severity and prognosis of severe brain injury.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Brain Injuries / Coma Subject: Brain Injuries / Coma Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Language: English Journal: J Trauma Nurs Clinical aspect: Diagnosis / Etiology / Prediction / Prognosis Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Brain Injuries / Coma Subject: Brain Injuries / Coma Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Language: English Journal: J Trauma Nurs Clinical aspect: Diagnosis / Etiology / Prediction / Prognosis Year: 2021
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