Hemodynamic differences by increasing low profile visualized intraluminal support (LVIS) stent local compaction across intracranial aneurysm orifice.
Interv Neuroradiol
; 26(5): 557-565, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-1455862
ABSTRACT
BACKGROUND:
The Low-profile Visualized Intraluminal Support device (LVIS) has been successfully used to treat cerebral aneurysm, and the push-pull technique has been used clinically to compact the stent across aneurysm orifice. Our aim was to exhibit the hemodynamic effect of the compacted LVIS stent.METHODS:
Two patient-specific aneurysm models were constructed from three-dimensional angiographic images. The uniform LVIS stent, compacted LVIS and Pipeline Embolization Device (PED) with or without coil embolization were virtually deployed into aneurysm models to perform hemodynamic analysis. Intra-aneurysmal flow parameters were calculated to assess hemodynamic differences among different models.RESULTS:
The compacted LVIS had the highest metal coverage across the aneurysm orifice (case 1, 46.37%; case 2, 67.01%). However, the PED achieved the highest pore density (case 1, 19.56 pores/mm2; case 2, 18.07 pores/mm2). The compacted LVIS produced a much higher intra-aneurysmal flow reduction than the uniform LVIS. The PED showed a higher intra-aneurysmal flow reduction than the compacted LVIS in case 1, but the results were comparable in case 2. After stent placement, the intra-aneurysmal flow was further reduced as subsequent coil embolization. The compacted LVIS stent with coils produced a similar reduction in intra-aneurysmal flow to that of the PED.CONCLUSIONS:
The combined characteristics of stent metal coverage and pore density should be considered when assessing the flow diversion effects of stents. More intra-aneurysmal flow reductions could be introduced by compacted LVIS stent than the uniform one. Compared with PED, compacted LVIS stent may exhibit a flow-diverting effect comparable to that of the PED.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Subarachnoid Hemorrhage
/
Stents
/
Intracranial Aneurysm
/
Embolization, Therapeutic
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Interv Neuroradiol
Journal subject:
Neurology
/
Radiology
Year:
2020
Document Type:
Article
Affiliation country:
1591019920952903
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