How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
Mycopathologia
; 186(6): 877-882, 2021 Dec.
Article
in English
| MEDLINE | ID: covidwho-1460405
ABSTRACT
Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron in circulation; and endothelial injury related to abundance glucose regulated protein 78 (GRP78), which are present in severe COVID-19, could favor Mucorales infection. In this short communication, we summarized how the dysregulated iron homeostasis in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection benefits Mucorales.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Mucorales
/
Mucormycosis
Limits:
Humans
Language:
English
Journal:
Mycopathologia
Year:
2021
Document Type:
Article
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