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Improved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a validated high-fidelity coupled radiation-CFD code.
Buchan, Andrew G; Yang, Liang; Welch, David; Brenner, David J; Atkinson, Kirk D.
  • Buchan AG; School of Engineering and Materials Science, Queen Mary University of London, E1 4NS, London, UK. a.buchan@qmul.ac.uk.
  • Yang L; School of Water, Energy and Environment (SWEE), Cranfield University, Bedford, MK43 0AL, UK.
  • Welch D; Center for Radiological Research, Columbia University Irving Medical Center, New York, NY, USA.
  • Brenner DJ; Center for Radiological Research, Columbia University Irving Medical Center, New York, NY, USA.
  • Atkinson KD; Faculty of Energy Systems and Nuclear Science, Ontario Tech University, Oshawa, Ontario, L1G 0C5, Canada.
Sci Rep ; 11(1): 19930, 2021 10 07.
Article in English | MEDLINE | ID: covidwho-1462026
ABSTRACT
Transmission of SARS-CoV-2 by aerosols has played a significant role in the rapid spread of COVID-19 across the globe. Indoor environments with inadequate ventilation pose a serious infection risk. Whilst vaccines suppress transmission, they are not 100% effective and the risk from variants and new viruses always remains. Consequently, many efforts have focused on ways to disinfect air. One such method involves use of minimally hazardous 222 nm far-UVC light. Whilst a small number of controlled experimental studies have been conducted, determining the efficacy of this approach is difficult because chamber or room geometry, and the air flow within them, influences both far-UVC illumination and aerosol dwell times. Fortunately, computational multiphysics modelling allows the inadequacy of dose-averaged assessment of viral inactivation to be overcome in these complex situations. This article presents the first validation of the WYVERN radiation-CFD code for far-UVC air-disinfection against survival fraction measurements, and the first measurement-informed modelling approach to estimating far-UVC susceptibility of viruses in air. As well as demonstrating the reliability of the code, at circa 70% higher, our findings indicate that aerosolized human coronaviruses are significantly more susceptible to far-UVC than previously thought.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Ultraviolet Rays / Disinfection / Coronavirus Infections / Coronavirus 229E, Human / Coronavirus OC43, Human / Virus Inactivation Type of study: Prognostic study Limits: Humans Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-99204-0

Full text: Available Collection: International databases Database: MEDLINE Main subject: Ultraviolet Rays / Disinfection / Coronavirus Infections / Coronavirus 229E, Human / Coronavirus OC43, Human / Virus Inactivation Type of study: Prognostic study Limits: Humans Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-99204-0