COVID-19 survivors with calcineurin-inhibitors-treated rheumatoid arthritis.

Kobayashi, Hiroshi; Hirai, Yuji; Aoki, Akiko

Kobayashi, Hiroshi; Hirai, Yuji; Aoki, Akiko.

Kobayashi H; Department of Rheumatology, Tokyo Medical University Hachioji Medical Center, Hachioji, Tokyo, Japan.
Hirai Y; Department of Infectious Diseases, Tokyo Medical University, Hachioji Medical Center, Hachioji, Tokyo, Japan.
Aoki A; Department of Rheumatology, Tokyo Medical University Hachioji Medical Center, Hachioji, Tokyo, Japan.

Mod Rheumatol Case Rep ; 6(1): 10-13, 2022 01 07.

Article in English | MEDLINE | ID: covidwho-1462426

ABSTRACT

ABSTRACT

We report two cases recovered from coronavirus disease 2019 with rheumatoid arthritis which had been in remission or low disease activity by taking calcineurin inhibitor (CNI). Both cases had moderate to severe pneumonia treated with intravenous dexamethasone or in the severe case remdesivir in addition to it. These cases suggest that the use of CNI may have affected the improvement of severe pneumonia.

Subject(s)

Arthritis, Rheumatoid; COVID-19 Drug Treatment; Calcineurin Inhibitors; Adenosine Monophosphate/analogs & derivatives; Adenosine Monophosphate/therapeutic use; Alanine/analogs & derivatives; Alanine/therapeutic use; Arthritis, Rheumatoid/drug therapy; Calcineurin; Calcineurin Inhibitors/therapeutic use; Dexamethasone/therapeutic use; Humans; Survivors

Keywords

Coronavirus disease 2019; calcineurin inhibitor; pneumonia; rheumatoid arthritis; risk factors

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Arthritis, Rheumatoid / Calcineurin Inhibitors / COVID-19 Drug Treatment Type of study: Case report / Prognostic study Limits: Humans Language: English Journal: Mod Rheumatol Case Rep Year: 2022 Document Type: Article Affiliation country: Mrcr

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