Your browser doesn't support javascript.
Transfusion profile, clinical characteristics, comorbidities and outcomes of 3014 hospitalized patients diagnosed with COVID-19 in Brazil.
Dalmazzo, Leandro Felipe Figueiredo; de Almendra Freitas, Alyne Ferreira; Alves, Brunna Eulálio; Cardoso, Diogo Kloppel; de Carvalho, Eduardo Ferro; Akil, Fabiana; da Cunha Vieira Perini, Fernanda; Pires, Karina Todeschini; de Aguiar, Ludmila Coutinho; Moraes, Mara Cabral; Madeira, Maria Isabel Ayrosa; Alves, Pablo Raphael Gomiero; Watanabe, Ruth Helena Perdiz; da Silva Sá Teixeira, Silvia Helena; Pereira, Tatiana Covas; de Lourdes Rosa Pessoa, Viviani; Vieira, Sérgio Domingos.
  • Dalmazzo LFF; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • de Almendra Freitas AF; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Alves BE; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Cardoso DK; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • de Carvalho EF; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Akil F; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • da Cunha Vieira Perini F; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Pires KT; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • de Aguiar LC; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Moraes MC; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Madeira MIA; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Alves PRG; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Watanabe RHP; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • da Silva Sá Teixeira SH; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Pereira TC; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • de Lourdes Rosa Pessoa V; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
  • Vieira SD; Grupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Vox Sang ; 116(9): 983-989, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1462885
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF hospitalized patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
hospitalized patients
2. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
3. Hospitals LOCATION_OF Retrospective Studies
Subject
Hospitals
Predicate
LOCATION_OF
Object
Retrospective Studies
4. Cessation of life PROCESS_OF Patients
Subject
Cessation of life
Predicate
PROCESS_OF
Object
Patients
5. Patients LOCATION_OF Fresh frozen plasma
Subject
Patients
Predicate
LOCATION_OF
Object
Fresh frozen plasma
6. Blood product TREATS Patients
Subject
Blood product
Predicate
TREATS
Object
Patients
7. Blood Transfusion TREATS Patients
Subject
Blood Transfusion
Predicate
TREATS
Object
Patients
8. Cryoprecipitate TREATS Patients
Subject
Cryoprecipitate
Predicate
TREATS
Object
Patients
9. COVID-19 PROCESS_OF hospitalized patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
hospitalized patients
10. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
11. Hospitals LOCATION_OF Retrospective Studies
Subject
Hospitals
Predicate
LOCATION_OF
Object
Retrospective Studies
12. Cessation of life PROCESS_OF Patients
Subject
Cessation of life
Predicate
PROCESS_OF
Object
Patients
13. Patients LOCATION_OF Fresh frozen plasma
Subject
Patients
Predicate
LOCATION_OF
Object
Fresh frozen plasma
14. Blood product TREATS Patients
Subject
Blood product
Predicate
TREATS
Object
Patients
15. Blood Transfusion TREATS Patients
Subject
Blood Transfusion
Predicate
TREATS
Object
Patients
16. Cryoprecipitate TREATS Patients
Subject
Cryoprecipitate
Predicate
TREATS
Object
Patients
ABSTRACT

BACKGROUND:

The novel coronavirus disease-2019 (COVID-19) caused a sudden and unexpected increase in the number of hospital admissions and deaths worldwide. The impact of social distancing on blood stocks was significant. Data on the use of blood products by patients with COVID-19 are scarce. MATERIAL AND

METHODS:

A retrospective observational study was conducted by analysing the medical records of 3014 hospitalized COVID-19 patients in 16 Brazilian hospitals. Individual data related to clinical, laboratory and transfusion characteristics and outcomes of these patients were collected. Patients characteristics association with mortality and transfusion need were tested independently by logistic regression models.

RESULTS:

Patients mean age was 57·6 years. In 2298 (76·2%) patients, there was an underlying clinical comorbidity. A total of 1657 (55%) patients required admission to intensive care unit (ICU), and 943 (31%) patients required ventilatory support and orotracheal intubation (OTI). There was a total of 471 (15·6%) deaths among all patients. 325 patients (10·7%) required blood transfusion; 3187 blood products were transfused 1364 red blood cells in 303 patients, 1092 platelet units in 78 patients, 303 fresh frozen plasma in 49 patients and 423 cryoprecipitates in 21 patients. The mortality among patients who received transfusion was substantially higher than that among the total study population.

CONCLUSION:

Need for transfusion was low in COVID-19 patients, but significantly higher in patients admitted to ICU and in those who needed OTI. Knowledge of the transfusion profile of these patients allows better strategies for maintaining the blood stocks of hospitals during the pandemic.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: COVID-19 Subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Language: English Journal: Vox Sang Year: 2021

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: COVID-19 Subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Language: English Journal: Vox Sang Year: 2021
...