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Haematuria, a widespread petechial rash, and headaches following the Oxford AstraZeneca ChAdOx1 nCoV-19 Vaccination.
Waraich, Ammar; Williams, George.
  • Waraich A; Department of Acute Medicine, Worcestershire Acute Hospitals NHS Trust, Worcester, Worcestershire, England, UK ammarwaraich@gmail.com.
  • Williams G; Department of Acute Medicine, Worcestershire Acute Hospitals NHS Trust, Worcester, Worcestershire, England, UK.
BMJ Case Rep ; 14(10)2021 Oct 07.
Article in English | MEDLINE | ID: covidwho-1462938
ABSTRACT
With increasing presentations of headaches following COVID-19 vaccination, we present one of the UK's earliest proven cases of vaccine-induced thrombotic thrombocytopaenia (VITT), with the aim of giving colleagues a case to compare other patients against. Our patient was a 48-year-old man who presented with frank haematuria, a widespread petechial rash, and headaches, 2 weeks after receiving the first dose of the Oxford AstraZeneca ChAdOx1 nCoV-19 vaccine. He had a platelet count of 14×109/L and an extensive cerebral venous sinus thrombosis (CVST) with subarachnoid haemorrhage on imaging. He developed localising neurological signs and experienced a cardiopulmonary arrest. He was successfully resuscitated and transferred to a tertiary care centre for urgent thrombectomy. This case illustrates how the diagnosis of VITT should be based on the platelet count and imaging-and how patients with VITT should be cared for in centres with urgent neurosurgical and interventional radiology services.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sinus Thrombosis, Intracranial / Exanthema / COVID-19 Type of study: Case report Topics: Vaccines Limits: Humans / Male / Middle aged Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-245440

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sinus Thrombosis, Intracranial / Exanthema / COVID-19 Type of study: Case report Topics: Vaccines Limits: Humans / Male / Middle aged Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-245440