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Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021.
Molenkamp, Richard; Fanoy, Ewout; Derickx, Leonie; de Groot, Theun; Jonges, Marcel; Leenstra, Tjalling; Nijhuis, Roel; Pas, Suzan; Vahidnia, Ali; von Wintersdorff, Christian; Mulder, Bert; Koopmans, Marion.
  • Molenkamp R; Department of Viroscience, Erasmus MC, Rotterdam, the Netherlands.
  • Fanoy E; Public Health Service Rotterdam-Rijnmond, Rotterdam, the Netherlands.
  • Derickx L; Public Health Service Gelderland-Zuid, Nijmegen, the Netherlands.
  • de Groot T; Department of Clinical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.
  • Jonges M; Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
  • Leenstra T; Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.
  • Nijhuis R; Laboratory for Medical Microbiology and Medical Immunology, Meander Medical Center, Amersfoort, the Netherlands.
  • Pas S; Microvida Laboratory for Medical Microbiology, Amphia Hospital, Breda, the Netherlands.
  • Vahidnia A; Testing Agency, Ministry of Health, Welfare and Sport, Zeist, the Netherlands.
  • von Wintersdorff C; Department of Medical Microbiology, Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.
  • Mulder B; Department of Clinical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.
  • Koopmans M; Department of Viroscience, Erasmus MC, Rotterdam, the Netherlands.
Euro Surveill ; 26(40)2021 10.
Article in English | MEDLINE | ID: covidwho-1463432
ABSTRACT
We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Variants Limits: Humans Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.Es.2021.26.40.2100921

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Variants Limits: Humans Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.Es.2021.26.40.2100921