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[A retrospective safety study on screening of the samples in the clinical biobank of Beijing Hospital].
Li, H X; Tang, X K; Xu, S Y; Luo, X M; Sun, G Y; Xu, H T; Zhang, P J; Xiao, F.
  • Li HX; Clinical Biobank, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Tang XK; Clinical Biobank, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Xu SY; Clinical Biobank, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Luo XM; Beijing Hospital, National Center of Gerontology, the MOH Key Laboratory of Geriatrics, Beijing 100730, China.
  • Sun GY; Clinical Biobank, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Xu HT; Department of Clinical Laboratory, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Zhang PJ; Department of Scientific Research Administration, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
  • Xiao F; Clinical Biobank, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Yu Fang Yi Xue Za Zhi ; 55(9): 1149-1152, 2021 Sep 06.
Article in Chinese | MEDLINE | ID: covidwho-1463876
ABSTRACT
To investigate whether the laboratory specimens preserved in Beijing Hospital Biobank during a specific period had been contaminated by SARS-Cov-2 through a cross-sectional study, and to establish a retrospective biobank safety screening system. Laboratory specimens were collected from the Department of Respiratory and Critical Care Medicine and the Fever Clinic of Beijing Hospital from November 1, 2019 to January 22, 2020, nucleic acid and serological antibody testing were performed for SARS-CoV-2 in these specimens (including 79 serum, 20 urine, 42 feces and 21 bronchoalveolar lavage fluid specimens). The safety of the stored samples during this period was defined by negative and positive results. Both the nucleic acid test and serological antibody test showed negative for SARS-CoV-2, indicating that these specimens were safely stored in the biobank. High-risk specimens collected in our hospital during the early stage of the COVID-19 outbreak are free of SARS-CoV-2, and a safety screening strategy for the clinical biobank is established to ensure the biosafety of these samples.
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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Biological Specimen Banks / COVID-19 Subject: Biological Specimen Banks / COVID-19 Type of study: Diagnostic study / Observational study / Prevalence study / Risk factors / Screening study Language: Chinese Journal: Zhonghua Yu Fang Yi Xue Za Zhi Clinical aspect: Etiology Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Biological Specimen Banks / COVID-19 Subject: Biological Specimen Banks / COVID-19 Type of study: Diagnostic study / Observational study / Prevalence study / Risk factors / Screening study Language: Chinese Journal: Zhonghua Yu Fang Yi Xue Za Zhi Clinical aspect: Etiology Year: 2021
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