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Humoral and cellular immunity and the safety of COVID-19 vaccines: a summary of data published by 21 May 2021.
Xu, Kun; Dai, Lianpan; Gao, George F.
  • Xu K; Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, The First Affiliated Hospital, Hainan Medical University, Hainan 571199, China.
  • Dai L; Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, The First Affiliated Hospital, Hainan Medical University, Hainan 571199, China.
  • Gao GF; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Int Immunol ; 33(10): 529-540, 2021 09 25.
Article in English | MEDLINE | ID: covidwho-1575943
ABSTRACT
Coronavirus disease 2019 (COVID-19) has caused millions of deaths, and serious consequences to public health, economies and societies. Rapid responses in vaccine development have taken place since the isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the release of the viral genome sequence. By 21 May 2021, 101 vaccines were under clinical trials, and published data were available for 18 of them. Clinical study results from some vaccines indicated good immunogenicity and acceptable reactogenicity. Here, we focus on these 18 vaccines that had published clinical data to dissect the induced humoral and cellular immune responses as well as their safety profiles and protection efficacy.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunity, Humoral / COVID-19 Vaccines / COVID-19 / Immunity, Cellular Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Int Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article Affiliation country: Intimm

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunity, Humoral / COVID-19 Vaccines / COVID-19 / Immunity, Cellular Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Int Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article Affiliation country: Intimm