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Reactivation of herpes simplex keratitis following vaccination for COVID-19.
Richardson-May, James; Rothwell, Alice; Rashid, Mohammed.
  • Richardson-May J; Ophthalmology, University Hospital Southampton NHS Foundation Trust, Southampton, UK jamesrichardsonmay@gmail.com.
  • Rothwell A; Ophthalmology, University Hospitals Dorset NHS Foundation Trust, Bournemouth, UK.
  • Rashid M; Ophthalmology, University Hospitals Dorset NHS Foundation Trust, Bournemouth, UK.
BMJ Case Rep ; 14(9)2021 Sep 07.
Article in English | MEDLINE | ID: covidwho-1467682
ABSTRACT
An 82-year-old man with a history of herpes simplex keratitis 40 years previously presented with recurrence, 1 day following vaccination for novel COVID-19. His condition worsened despite topical treatment with ganciclovir gel. A diagnosis of herpetic stromal keratitis was made, requiring systemic aciclovir, topical prednisolone, moxifloxacin and atropine, and oral doxycycline. He improved clinically on treatment, with some residual corneal scarring. Visual acuity improved from 6/36 corrected at presentation, to 6/24 following treatment. Clearly, public and personal health benefits from vaccination are hugely important and we would not suggest avoiding vaccination in such patients. It is, however, important for ophthalmic providers to be aware of the rare potential for reactivation of herpetic eye disease following vaccination to enable prompt diagnosis and treatment.
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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Keratitis, Herpetic / COVID-19 Subject: Keratitis, Herpetic / COVID-19 Type of study: Case report / Diagnostic study Language: English Clinical aspect: Therapy Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Keratitis, Herpetic / COVID-19 Subject: Keratitis, Herpetic / COVID-19 Type of study: Case report / Diagnostic study Language: English Clinical aspect: Therapy Year: 2021
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