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CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm.
Acevedo, Alice-Christin; Zoller, Michael; Scharf, Christina; Liebchen, Uwe; Irlbeck, Michael; Schroeder, Ines.
  • Acevedo AC; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
  • Zoller M; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
  • Scharf C; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
  • Liebchen U; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
  • Irlbeck M; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
  • Schroeder I; Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Case Rep Crit Care ; 2021: 9937499, 2021.
Article in English | MEDLINE | ID: covidwho-1467759
ABSTRACT
Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report describes a 59-year-old SARS-CoV-2-positive patient with severe ARDS. Due to severe hyperinflammation with concomitant hemodynamic instability and progressive renal failure, combination of continuous renal replacement and CytoSorb® hemoadsorption therapy was initiated. Treatment resulted immediately in a control of the hyperinflammatory response. Simultaneously, lung function continued to improve accompanied by profound hemodynamic stabilization. We report the successful utilization of CytoSorb® hemoadsorption in the treatment of a patient with SARS-CoV-2-induced cytokine storm syndrome.

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Type of study: Case report / Observational study Language: English Journal: Case Rep Crit Care Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Type of study: Case report / Observational study Language: English Journal: Case Rep Crit Care Year: 2021
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