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The incidence and admission rate for first-episode psychosis in young people before and during the COVID-19 pandemic in Melbourne, Australia.
O'Donoghue, Brian; Collett, Hannah; Boyd, Sophie; Zhou, Yuanna; Castagnini, Emily; Brown, Ellie; Street, Rebekah; Nelson, Barnaby; Thompson, Andrew; McGorry, Patrick.
  • O'Donoghue B; Orygen, Parkville, VIC, Australia.
  • Collett H; Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
  • Boyd S; Orygen, Parkville, VIC, Australia.
  • Zhou Y; Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
  • Castagnini E; Orygen, Parkville, VIC, Australia.
  • Brown E; Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
  • Street R; Orygen, Parkville, VIC, Australia.
  • Nelson B; Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
  • Thompson A; Orygen, Parkville, VIC, Australia.
  • McGorry P; Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
Aust N Z J Psychiatry ; 56(7): 811-817, 2022 07.
Article in English | MEDLINE | ID: covidwho-1470558
ABSTRACT

OBJECTIVE:

The COVID-19 pandemic has had a profound effect on global mental health, with one-third of infected individuals developing a psychiatric or neurological disorder 6 months after infection. The risk of infection and the associated restrictions introduced to reduce the spread of the virus have also impacted help-seeking behaviours. Therefore, this study aimed to determine whether there was a difference during the COVID-19 pandemic in the treated incidence of psychotic disorders and rates of admission to hospital for psychosis (including involuntary admission).

METHODS:

Incident cases of first-episode psychosis in young people, aged 15 to 24, at an early intervention service in Melbourne from an 8-month period before the pandemic were compared with rates during the pandemic. Hospital admission rates for these periods were also compared.

RESULTS:

Before the pandemic, the annual incidence of first-episode psychosis was 104.5 cases per 100,000 at-risk population, and during the pandemic it was 121.9 (incidence rate ratio = 1.14, 95% confidence interval = [0.92, 1.42], p = 0.24). Immediately after the implementation of restrictions, there was a non-significant reduction in the treated incidence (incidence rate ratio = 0.80, 95% confidence interval = [0.58, 1.09]), which was followed by a significant increase in the treated incidence in later months (incidence rate ratio = 1.94, 95% confidence interval = [1.52, 2.49]; incidence rate ratio = 1.64, 95% confidence interval = [1.25, 2.16]). Before the pandemic, 37.3% of young people with first-episode psychosis were admitted to hospital, compared to 61.7% during the pandemic (odds ratio = 2.71, 95% confidence interval = [1.73, 4.24]). Concerning the legal status of the admissions, before the pandemic, 27.3% were admitted involuntarily to hospital, compared to 42.5% during the pandemic (odds ratio = 1.97, 95% confidence interval = [1.23, 3.14]).

CONCLUSION:

There was a mild increase, which did not reach statistical significance, in the overall incidence of first-episode psychosis; however, the pattern of presentations changed significantly, with nearly twice as many cases presenting in the later months of the restrictions. There was a significant increase in both voluntary and involuntary admissions, and the possible explanations for these findings are discussed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Psychotic Disorders / COVID-19 Type of study: Observational study / Prognostic study / Qualitative research Limits: Adolescent / Humans Language: English Journal: Aust N Z J Psychiatry Year: 2022 Document Type: Article Affiliation country: 00048674211053578

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Psychotic Disorders / COVID-19 Type of study: Observational study / Prognostic study / Qualitative research Limits: Adolescent / Humans Language: English Journal: Aust N Z J Psychiatry Year: 2022 Document Type: Article Affiliation country: 00048674211053578