Lessons from vaccine-induced immune thrombotic thrombocytopenia
Nature reviews. Immunology
; : 1-3, 2021.
Article
in English
| EuropePMC | ID: covidwho-1472925
ABSTRACT
Adenoviral vector vaccines are effective against SARS-CoV-2 but have been associated with a rare side effect termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Here, we discuss our understanding of how vaccine-induced antibodies to platelet factor 4 (PF4) form immune complexes that activate platelets and trigger the thrombotic events seen in VITT. Here, John Kelton and colleagues provide an overview of vaccine-induced immune thrombotic thrombocytopenia (VITT), a very rare complication that has been observed following vaccination with adenoviral vector-based COVID-19 vaccines.
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Collection:
Databases of international organizations
Database:
EuropePMC
Topics:
Vaccines
Language:
English
Journal:
Nature reviews. Immunology
Year:
2021
Document Type:
Article
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