Clinical presentation of neuroendocrine cancer metastasis to an anterior clinoid process meningioma invading superior orbital fissure. A case report.
Folia Neuropathol
; 59(3): 322-326, 2021.
Article
in English
| MEDLINE | ID: covidwho-1478320
ABSTRACT
Metastasis to a meningioma is an uncommon phenomenon however reported in the literature. Meningiomas are common primary intracranial tumours which most frequently occur to be a recepient of metastases. A 66-year-old female presented with rapid development of visual acuity and visual field loss in the right eye with ipsilateral oculomotor nerve palsy. Magnetic resonance imaging (MRI) showed well-defined tumour intensely enhanced with contrast like a typical skull base meningioma. The neuropathological examination revealed two different morphological fragments of the tumour. In the cell-rich part of the tumour, immunopositivity for CK, chromogranin, and SY were detected. The less cellular portion of the tumour, immunopositivity to epithelial membrane antigen (EMA) and vimentin were detected. To our knowledge, we present the first rare metastasis of neuroendocrine carcinoma to the medial sphenoid meningioma that preceded the clinical symptoms of systemic neuroendocrine carcinoma.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Orbital Neoplasms
/
Carcinoma, Neuroendocrine
/
Meningeal Neoplasms
/
Meningioma
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Folia Neuropathol
Journal subject:
Neurology
/
Pathology
Year:
2021
Document Type:
Article
Affiliation country:
Fn.2021.109409
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