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Low mortality from COVID-19 at a nursing facility in France following a combined preventive and active treatment protocol.
Worcel, Alexandre; Ali, Bougacha M; Ramos-Pascual, Sonia; Stirling, Patrick; Chary, François G.
  • Worcel A; ELSAN, Clinique Conti, 3 Chemin des Trois Sources, L'Isle-Adam, France.
  • Ali BM; ELSAN, Clinique Conti, 3 Chemin des Trois Sources, L'Isle-Adam, France.
  • Ramos-Pascual S; ReSurg SA, Rue Saint-Jean 22, Nyon, Switzerland.
  • Stirling P; ReSurg SA, Rue Saint-Jean 22, Nyon, Switzerland.
  • Chary FG; Residence Médicalisée Zemgor, 35 Rue du Martray, Cormeilles-en-Parisis, France.
Ann Palliat Med ; 10(11): 11288-11300, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1478829
ABSTRACT

BACKGROUND:

The aim of this study was to retrospectively describe the evolution of symptoms, infections, and mortality at a nursing facility in France that had implemented a protocol for the prevention and treatment of COVID-19.

METHODS:

A database was created on 21 March 2020 to store all information related to residents, including co-morbidities, as well as COVID-19 symptoms, incidence, and mortality. Residents followed a COVID-19 protocol, consisting of preventive (administering vitamins and zinc, social distancing, and temperature checks) and active (antibiotics, anticoagulants, and corticosteroids) measures. RT-PCR and serology testing were performed on residents. A new coefficient, named the Zemgor coefficient, was calculated as the haemoglobin-to-albumin ratio at 2 time points 15 days apart, to monitor hypoxemia.

RESULTS:

In January 2020, the nursing facility housed 192 residents, 75 men and 117 women, aged 80±11. One or more co-morbidities were present in 94% of residents, with the most common being dementia. The COVID-19 protocol provided 61% of residents with anticoagulants, 51%with antibiotics, 21% with oxygen therapy, and 3% with corticosteroids. The COVID-19 incidence was 51% based on presence of COVID-19 symptoms, 35% based on positive RT-PCR (amongst residents tested for RT-PCR) and 41% based on positive serology (amongst residents tested for serology), and the COVID-19 mortality rate was 8%. The Zemgor coefficient was 0.049±0.053 for patients with hypoxemia compared to 0.011±0.041 for patients without hypoxemia (P=0.001).

CONCLUSIONS:

The protocol for the prevention and treatment of COVID-19 implemented at this nursing facility resulted in a COVID-19 incidence and mortality at the lower end of that reported by other nursing facilities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Journal: Ann Palliat Med Year: 2021 Document Type: Article Affiliation country: Apm-21-1707

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Journal: Ann Palliat Med Year: 2021 Document Type: Article Affiliation country: Apm-21-1707