A case of chronic systemic capillary leak syndrome (SCLS) exacerbated during SARS-CoV2 infection.

Concistrè, A; Alessandri, F; Rosato, E; Pugliese, F; Muscaritoli, M; Letizia, C

Concistrè, A; Alessandri, F; Rosato, E; Pugliese, F; Muscaritoli, M; Letizia, C.

Concistrè A; Department of Translational and Precision Medicine, University "Sapienza", Rome, Italy. claudio.letizia@uniroma1.it.

Eur Rev Med Pharmacol Sci ; 25(19): 5922-5927, 2021 Oct.

Article in English | MEDLINE | ID: covidwho-1478933

ABSTRACT

ABSTRACT

Systemic capillary leak syndrome (SCLS) is a very rare and lethal disease characterized by hemoconcentration and hypoalbuminemia caused by reversible plasma extravasation. The underlying cause for SCLS remains largely unknown and acute treatment has remained mainly supportive. Prophylaxis with intravenous immunoglobulin (IVIG) has been shown to successfully prevent further episodes in affected patients. We reported a case of SCLS in a patient who presented to our hospital with COVID-19 and developed profound shock.

Subject(s)

COVID-19/pathology; Capillary Leak Syndrome/pathology; COVID-19/complications; COVID-19/diagnostic imaging; Capillary Leak Syndrome/complications; Capillary Leak Syndrome/diagnostic imaging; Humans; Immunoglobulins, Intravenous/therapeutic use; Male; Middle Aged; Pneumonia/complications; Pneumonia/pathology; Shock/etiology; Shock/pathology; Tomography, X-Ray Computed

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Capillary Leak Syndrome / COVID-19 Type of study: Case report / Prognostic study Topics: Long Covid Limits: Humans / Male / Middle aged Language: English Journal: Eur Rev Med Pharmacol Sci Journal subject: Pharmacology / Toxicology Year: 2021 Document Type: Article Affiliation country: Eurrev_202110_26868

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