Fluorescence Immunoassay System Plays an Important Role in Timely Diagnosis of COVID-19 Infection
Health Science Journal
; 15(9):1-5, 2021.
Article
in English
| ProQuest Central | ID: covidwho-1479206
ABSTRACT
In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death. [...]there is giant demand for the COVID-19 tests. In samples without infected, since there is no target gene amplification, no increase in fluorescence signal can be detected. [...]nucleic acid detection is actually to determine whether there is novel coronavirus nucleic acid in the sample by detecting the accumulation of fluorescent signals. According to the principle of double-antibody sandwich method, using two antigen-specific antibodies to recognize and bind to different epitopes of a target antigen can greatly reduce the probability of cross-reaction, thereby effectively improving its specificity [1]. Positive detection of IgG in blood can be used as an indicator of infection and previous infection [8]. [...]an increase of IgM antibody indicates a recent acute infection, and an increase of IgG antibody indicates a previous infection.
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Collection:
Databases of international organizations
Database:
ProQuest Central
Language:
English
Journal:
Health Science Journal
Year:
2021
Document Type:
Article
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