Research Progress in Anti-Inflammatory Bioactive Substances Derived from Marine Microorganisms, Sponges, Algae, and Corals.
Mar Drugs
; 19(10)2021 Oct 14.
Article
in English
| MEDLINE | ID: covidwho-1485164
ABSTRACT
Inflammation is the body's defense reaction in response to stimulations and is the basis of various physiological and pathological processes. However, chronic inflammation is undesirable and closely related to the occurrence and development of diseases. The ocean gives birth to unique and diverse bioactive substances, which have gained special attention and been a focus for anti-inflammatory drug development. So far, numerous promising bioactive substances have been obtained from various marine organisms such as marine bacteria and fungi, sponges, algae, and coral. This review covers 71 bioactive substances described during 2015-2020, including the structures (65 of which), species sources, evaluation models and anti-inflammatory activities of these substances. This review aims to provide some reference for the research progress of marine-organism-derived anti-inflammatory metabolites and give more research impetus for their conversion to novel anti-inflammatory drugs.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Biological Products
/
Aquatic Organisms
/
Anti-Inflammatory Agents
Type of study:
Experimental Studies
Limits:
Animals
/
Humans
Language:
English
Journal subject:
Biology
/
Pharmacology
Year:
2021
Document Type:
Article
Affiliation country:
Md19100572
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