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Maternal and Neonatal Complications, Outcomes and Possibility of Vertical Transmission in Iranian Women with COVID-19.
Heidary, Zohreh; Kohandel Gargari, Omid; Fathi, Hanieh; Zaki-Dizaji, Majid; Ghaemi, Marjan; Hossein Rashidi, Batool.
  • Heidary Z; Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Kohandel Gargari O; Student Research Committee of Alborz University of Medical Sciences, Karaj, Iran.
  • Fathi H; Student Research Committee of Alborz University of Medical Sciences, Karaj, Iran.
  • Zaki-Dizaji M; Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
  • Ghaemi M; Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Hossein Rashidi B; Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med ; 24(9): 713-721, 2021 09 01.
Article in English | MEDLINE | ID: covidwho-1485772
ABSTRACT

BACKGROUND:

The emergence and fast spread of coronavirus disease 2019 (COVID-19) threatens the world as a new public health crisis. Little is known about its effects during pregnancy. This study aimed to investigate the clinical manifestations of COVID-19 on maternal and neonatal outcomes.

METHODS:

In this systematic review, PubMed, Scopus, Web of Science, and Google Scholar databases were searched focusing on pregnancy and perinatal outcomes of COVID-19.

RESULTS:

The initial search yielded 1236 articles, from which finally 21 unique studies, involving 151 pregnant women and 17 neonates, met the criteria. Mean ± SD age of included mothers and mean ± SD gestational age at admission were 30.6 ± 6.2 years and 30.8 ± 8.9 weeks, respectively. The common symptoms were fever, cough, fatigue, dyspnea and myalgia. The mortality rates of pregnant women and neonates were 28 out of 151 (18.5%) and 4 out of 17 (23.5%), respectively. Most of the neonates were preterm at the time of delivery. Three neonates had positive RT-PCR test on the first day after birth and three others on day two. On the average, neonate's PCR became positive on day 4 for the first time.

CONCLUSION:

Early diagnosis of COVID-19 is crucial due to the possibility of the prenatal complications. Strict prevention strategies may reduce the risk of mother to infant transmission.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / Infectious Disease Transmission, Vertical / COVID-19 Type of study: Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Country/Region as subject: Asia Language: English Journal: Arch Iran Med Year: 2021 Document Type: Article Affiliation country: Aim.2021.104

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / Infectious Disease Transmission, Vertical / COVID-19 Type of study: Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Country/Region as subject: Asia Language: English Journal: Arch Iran Med Year: 2021 Document Type: Article Affiliation country: Aim.2021.104