SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy.
Emerg Infect Dis
; 27(10): 2725-2728, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1486745
ABSTRACT
A 72-year-old immunocompromised man infected with severe acute respiratory syndrome coronavirus 2 received bamlanivimab monotherapy. Viral evolution was monitored in nasopharyngeal and blood samples by melting curve analysis of single-nucleotide polymorphisms and whole-genome sequencing. Rapid emergence of spike receptor binding domain mutations was found, associated with a compartmentalization of viral populations.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Topics:
Variants
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Emerg Infect Dis
Journal subject:
Communicable Diseases
Year:
2021
Document Type:
Article
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